Three new RelE-homologous mRNA interferases ofEscherichia colidifferentially induced by environmental stresses

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Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses

Prokaryotic toxin - antitoxin (TA) loci encode mRNA interferases that inhibit translation, either by cleaving mRNA codons at the ribosomal A site or by cleaving any RNA site-specifically. So far, seven mRNA interferases of Escherichia coli have been identified, four of which cleave mRNA by a translation-dependent mechanism. Here, we experimentally confirmed the presence of three novel TA loci i...

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ژورنال

عنوان ژورنال: Molecular Microbiology

سال: 2010

ISSN: 0950-382X,1365-2958

DOI: 10.1111/j.1365-2958.2009.06969.x